Methylation status and AP1 elements are involved in EBV-mediated miR-155 expression in EBV positive lymphoma cells
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- 作者：Qinyan Yina ; qyin@tulane.edu" class="auth_mail" title="E-mail the corresponding author ; Xia Wangb ; xwang4@tulane.edu" class="auth_mail" title="E-mail the corresponding author ; Claire Robertsb ; cfewell@tulane.edu" class="auth_mail" title="E-mail the corresponding author ; Erik K. Flemingtonb ; erik@tulane.edu" class="auth_mail" title="E-mail the corresponding author ; Joseph A. Laskya ; jlasky@tulane.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Epstein Barr Virus ; EBV ; MicroRNA ; MiRNA ; MiR-155 ; Pri-miR-155 ; AP1 ; DNA methylation ; LMPs ; EBNAs
- 刊名：Virology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：494
- 期：Complete
- 页码：158-167
- 全文大小：2399 K
文摘
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The DNA methylation of miR-155 CpG island regulates miR-155 expression in EBV-positive cells.
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AP1 signaling pathway is involved in EBV-mediated miR-155 activation.
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The regulation of miR-155 by EBV is dependent on more than one EBV gene or multiple cell signaling pathways.