Comparisons of dysphagia and quality of life (QOL) in comparable patients with HPV-positive oropharyngeal cancer receiving chemo-irradiation or cetuximab-irradiation
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- 作者：Stuart E. Samuelsa ; Yebin Taob ; Teresa Lydenc ; Marc Haxerc ; Matthew Spectord ; Kelly M. Malloyd ; Mark E. Princed ; Carol R. Bradfordd ; Francis P. Wordene ; Matthew Schipperf ; Avraham Eisbrucha ; eisbruch@umich.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Oropharyngeal cancer ; Quality of life ; Swallowing ; Cetuximab ; Chemo-RT
- 刊名：Oral Oncology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：54
- 期：Complete
- 页码：68-74
- 全文大小：628 K
文摘
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Outcome of matched patients with good-prognosis oropharyngeal cancer [HPV(+), treated on studies of chemo-RT and cetuximab-RT.
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Longitudinal evaluations of swallowing, observer and patient-reported dysphagia, and QOL, were made in through 12 months.
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No significant differences between the arms were observed.
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These data do not support replacing chemotherapy with cetuximab for treatment de-intensification.