Effect of estradiol on apoptosis, proliferation and steroidogenic enzymes in the testes of the toad Rhinella arenarum (Amphibia, Anura)
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- 作者：Marí ; a Florencia Scaia ; mflorenciascaia@bg.fcen.uba.ar" class="auth_mail" title="E-mail the corresponding author ; Marí ; a Clara Volonteri claravolonteri@bg.fcen.uba.ar" class="auth_mail" title="E-mail the corresponding author ; Silvia Cristina Czuchlej czuchlej@bg.fcen.uba.ar" class="auth_mail" title="E-mail the corresponding author ; Nora Raquel Ceballos nceballo@bg.fcen.uba.ar" class="auth_mail" title="E-mail the corresponding author
- 关键词：E2 ; estradiol ; CypP450c17 ; cytochrome P450 17α-hydroxylase-C17&ndash ; 20 lyase ; 3β-HSD/I ; 3β-hydroxysteroid dehydrogenase/isomerase ; RIA ; radioimmunoassay ; BO ; Bidder&rsquo ; s organ
- 刊名：General and Comparative Endocrinology
- 出版年：2015
- 出版时间：15 September 2015
- 年：2015
- 卷：221
- 期：Complete
- 页码：244-254
- 全文大小：4543 K
文摘
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Estradiol stimulates testicular apoptosis during the breeding season in male toads.
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Apoptosis occurs mostly in spermatocytes.
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Estradiol has no effect on testicular proliferation.
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Estradiol has no effect on the activity and expression of CypP450c17 in testes.
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Estradiol reduces the activity of 3β-HSD/I during the post reproductive season.