Vancomycin resistance has caused greater interest in the use of daptomycin.
Daptomycin lowers clinical failure rates compared with vancomycin in patients with Staphylococcus aureus-induced bacteraemia-infective endocarditis.
Daptomycin can also lower costs as it can reduce the length of stay.
This is more likely with outpatient parenteral antibiotic therapy.