• 作者：Jean-Guillaume Dillinger^a ; Alaa Saeed^a ; ¹ ; Vincent Spagnoli^a ; ¹ ; Claire Bal dit Sollier^b ; ¹ ; Georgios Sideris^a ; ¹ ; Stephane Manzo Silberman^a ; ¹ ; Sebastian Voicu^a ; ¹ ; Ludovic Drouet^b ; ¹ ; Patrick Henry^a ; ¹ ; ^{patrick.henry@lrb.aphp.fr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Aspirin ; Myocardial infarction ; Platelet reactivity ; P2Y12 inhibitors
• 刊名：Thrombosis Research
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：144
• 期：Complete
• 页码：56-61
• 全文大小：396 K

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Acute cardiovascular events including stent thrombosis are frequent after acute myocardial infarction

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Drug interaction, problems of absorption or unstable hemodynamics could lead to a decrease in effectiveness of antithrombotic therapy

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High platelet reactivity on aspirin and P2Y12i have never been studied in acute myocardial infarction

class="boldFont">What does this paper add?

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HPR-aspirin is frequent at the acute phase of myocardial infarction (23%)

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HPR-aspirin alone and HPR on both aspirin and P2Y12i are significantly associated with MACCE

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The occurrence of HPR-aspirin decreases over time following the acute event