PEDF attenuates insulin-dependent molecular pathways of glucose homeostasis in skeletal myocytes
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- 作者：Revathy Carnagarina ; b ; Arun M. Dharmarajana ; c ; Crispin R. Dassa ; b ; Crispin.Dass@curtin.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：PEDF ; Skeletal muscle ; Insulin resistance ; Glucose ; Akt
- 刊名：Molecular and Cellular Endocrinology
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：422
- 期：Complete
- 页码：115-124
- 全文大小：2209 K
文摘
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PEDF is evolving as a protein of metabolic dysregulation.
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PEDF attenuates critical signalling pathways involved in insulin-dependent glucose homeostasis.
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PEDF could serve as a potential therapeutic target to handle the insulin resistance of metabolic disorders.