The immediate effects of acoustic trauma on excitation and inhibition in the inferior colliculus: A Wiener-kernel analysis
详细信息 查看全文
- 作者：Amarins Nieske Heeringaa ; b ; amarinsh@umich.edu" class="auth_mail" title="E-mail the corresponding author ; Pim van Dijka ; b ; p.van.dijk@umcg.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Wiener kernels ; Inferior colliculus ; Acoustic trauma ; Singular value decomposition ; Guinea pig ; Inhibition ; Tinnitus ; Hyperacusis ; Auditory ; Nonlinearity
- 刊名：Hearing Research
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：331
- 期：Complete
- 页码：47-56
- 全文大小：3114 K
文摘
- class="listitem" id="list_ulist0010">
- class="label">•
Wiener kernels were used to study excitation and inhibition in the inferior colliculus.
- class="label">•
Acoustic trauma resulted in the loss of both excitatory and inhibitory components in high-CF units.
- class="label">•
Units tuned to frequencies within two octaves below the trauma frequency retained an excitatory response but lost inhibition.
- class="label">•
Reduced inhibition in the inferior colliculus may contribute to immediate noise-induced tinnitus and hyperacusis.