Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia
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- 作者：Guillaume Colleta ; b ; 1 ; Krzysztof Szadea ; b ; Witold Nowaka ; b ; Krzysztof Klimkiewicza ; b ; Bouchra El Hafny-Rahbia ; Karol Szczepaneka ; b ; 2 ; Daisuke Sugiyamac ; Kazimierz Weglarczyka ; Alexandra Foucault-Colleta ; 1 ; Alan Guicharda ; Andrzej Mazana ; b ; Mahdi Nadima ; Fabienne Fasania ; Nathalie Lamerant-Fayela ; Catherine Grillona ; Sté ; phane Petouda ; Jean-Claude Beloeila ; Alicja Jozkowiczb ; d ; Jozef Dulakb ; d ; jozef.dulak@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Claudine Kiedaa ; d ; claudine.kieda@cnrs-orleans.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endothelial precursor cells ; Pathologic angiogenesis/vasculogenesis ; Tumor targeting ; Cell gene therapy
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 January 2016
- 年：2016
- 卷：370
- 期：2
- 页码：345-357
- 全文大小：4030 K
文摘
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A model of tumor homing-cell based targeting of pathologic angiogenesis.
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Defined endothelial precursor cells selectively seeking into the tumor vessels.
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Potential cell therapy normalizing tumor angiogenesis by endothelial precursor cells.
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Tumor microenvironment modification by functional angiogenesis/vasculogenesis.
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Endothelial precursor cells as carriers of therapeutic agents to tumor.