A new antimicrobial protein from the anterior midgut of Triatoma infestans mediates Trypanosoma cruzi establishment by controlling the microbiota
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- 作者：Diego S. Buarquea ; diego_bq@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Cí ; cera M. Gomesa ; cicera_gomes@uol.com.br" class="auth_mail" title="E-mail the corresponding author ; Ricardo N. Araú ; job ; ricnaraujo@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Marcos H. Pereirab ; marcoshp@icb.ufmg.br" class="auth_mail" title="E-mail the corresponding author ; Roberta C. Ferreirac ; robertac@cpqrr.fiocruz.br" class="auth_mail" title="E-mail the corresponding author ; Alessandra A. Guarneric ; guarneri@cpqrr.fiocruz.br" class="auth_mail" title="E-mail the corresponding author ; Aparecida S. Tanakaa ; tanaka.bioq@epm.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antimicrobial properties ; Bacteria ; Midgut ; Parasite ; Triatoma infestans ; Trypanosoma cruzi
- 刊名：Biochimie
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：123
- 期：Complete
- 页码：138-143
- 全文大小：777 K
文摘
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A new protein (TiAP) from anterior midgut of Triatoma infestans is modulated by Trypanosoma cruzi.
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TiAP doesn't interfere in the viability of T. cruzi trypomastigotes.
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TiAP is able to control bacterial load inside anterior midgut of T. infestans.
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TiAP is important in maintenance of T. cruzi – microbiota balance in the vector.