White matter structural connectivity changes correlate with epilepsy duration in temporal lobe epilepsy
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- 作者：Sharon Chianga ; 1 ; sc4712@rice.edu" class="auth_mail" title="E-mail the corresponding author ; Harvey S. Levinb ; e ; hlevin@bcm.edu" class="auth_mail" title="E-mail the corresponding author ; Elisabeth Wildeb ; ewilde@bcm.edu" class="auth_mail" title="E-mail the corresponding author ; Zulfi Haneefc ; d ; 1 ; zulfi.haneef@bcm.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Temporal lobe epilepsy ; Diffusion tensor imaging ; Progression ; Mean diffusivity ; Fractional anisotropy
- 刊名：Epilepsy Research
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：37-46
- 全文大小：821 K
文摘
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DTI analysis in TLE showed increased MD and decreased FA of hippocampal connections.
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Increased left hippocampal MD correlated strongly with epilepsy duration in left TLE.
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Right hippocampal MD had the strongest discriminatory ability between left and right TLE.
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We find a reduction in white matter integrity with increasing duration of TLE that is distinct based on TLE laterality.