Nanobodies as therapeutics: big opportunities for small antibodies
详细信息 查看全文
- 作者：Sophie Steeland1 ; 2Author Vitae ; Roosmarijn E. Vandenbroucke1 ; 2 ; 3Author Vitae ; Claude Libert1 ; 2 ; 3 ; Claude.Libert@irc.VIB-UGent.be" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 刊名：Drug Discovery Today
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：21
- 期：7
- 页码：1076-1113
- 全文大小：3725 K
文摘
- class="listitem" id="list_lis0005">
- class="label">•
Nanobodies (Nbs) are camelid-derived single-domain antibodies.
- class="label">•
Nbs have powerful binding and inhibitory capacity with great therapeutic potential.
- class="label">•
Nbs are used in cancer, infections, inflammation and neurodegeneration.
- class="label">•
Several clinical trials with Nbs are on-going.