Ruthenium(II)-arene complexes with dibenzoylmethane induce apoptotic cell death in multiple myeloma cell lines
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- 作者：Riccardo Pettinaria ; riccardo.pettinari@unicam.it" class="auth_mail" title="E-mail the corresponding author ; Fabio Marchettib ; Agnese Petrinia ; Claudio Pettinaria ; Giulio Lupidia ; Belé ; n Ferná ; ndezc ; Antonio Rodrí ; guez Dié ; guezc ; Giorgio Santonia ; Massimo Nabissia
- 关键词：Ru(II)-arene ; Dibenzoylmethane ; RAPTA ; DNA interaction studies ; Protein binding studies ; Multiple myeloma
- 刊名：Inorganica Chimica Acta
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：454
- 期：Complete
- 页码：139-148
- 全文大小：1244 K
文摘
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Synthesis of Ru(II)-arene dibenzoylmethane complexes.
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Analytical, spectral and X-ray characterization.
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Antitumor activity in vitro against U266 and RPMI human multiple myeloma cell lines.
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DNA interaction studies.
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Protein binding studies.