Developmental Patterning: Putting the Squeeze on Mis-specified Cells

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• 作者：Yu-ichiro Nakajima ; Matthew C. Gibson ; ^{MG2@stowers.org" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Current Biology
• 出版年：2016
• 出版时间：7 March 2016
• 年：2016
• 卷：26
• 期：5
• 页码：R204-R206
• 全文大小：639 K

文摘

Widely implicated in human disease, abnormal cellular cysts reflect dramatic defects in the maintenance of epithelial integrity. A new study reports that epithelial cysts may arise as a surprisingly general consequence of clonal defects in the specification of cell identity.