Waning protection of influenza vaccine against mild laboratory confirmed influenza A(H3N2) and B in Spain, season 2014-15
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- 作者：Alin Gherasima ; amgherasim@externos.isciii.es" class="auth_mail" title="E-mail the corresponding author ; Francisco Pozob ; pacopozo@isciii.es" class="auth_mail" title="E-mail the corresponding author ; Salvador de Mateoa ; c ; smateo@isciii.es" class="auth_mail" title="E-mail the corresponding author ; Inma Aspiritxaga Gamarrad ; enfer4bi-san@euskadi.eus" class="auth_mail" title="E-mail the corresponding author ; Manuel Garcí ; a-Cenozc ; e ; mgcenoz@cfnavarra.es" class="auth_mail" title="E-mail the corresponding author ; Tomas Vegaf ; VegAloTo@jcyl.es" class="auth_mail" title="E-mail the corresponding author ; Eva Martí ; nezg ; emochoa@larioja.org" class="auth_mail" title="E-mail the corresponding author ; Jaume Gimé ; nezh ; jgimenez@dgsanita.caib.es" class="auth_mail" title="E-mail the corresponding author ; Daniel Castrillejoi ; dcastr01@melilla.es" class="auth_mail" title="E-mail the corresponding author ; Amparo Larrauria ; c ; alarrauri@isciii.es" class="auth_mail" title="E-mail the corresponding author ; cycEVA team ; the VEVA Working Group1
- 关键词：Influenza ; Influenza-like illness ; Influenza vaccine ; Test negative case&ndash ; control design ; Vaccine effectiveness ; Waning protection
- 刊名：Vaccine
- 出版年：2016
- 出版时间：29 April 2016
- 年：2016
- 卷：34
- 期：20
- 页码：2371-2377
- 全文大小：778 K
文摘
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The 2014/15 influenza season in Spain was dominated by drifted A(H3N2) virus.
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The influenza vaccine effectiveness was low against influenza A(H3N2) and moderate against B virus.
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The influenza vaccine effectiveness decreased in late epidemic stage and with time since vaccination.
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The decrease of IVE was slower and milder against influenza B than against influenza A(H3N2).
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We highlight the importance of the influenza vaccination especially in population risk groups.