Multicentric study of the effect of pre-analytical variables in the quality of plasma samples stored in biobanks using different complementary proteomic methods
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- 作者：Jesú ; s Mateosa ; 1 ; Isabel Carneirob ; Fernando Corralesc ; Felix Elortzad ; Alberto Paradelae ; Manuel Sá ; nchez del Pinof ; Ibon Ilorod ; Miguel Marcillae ; Maria Isabel Morac ; Luz Valerof ; Sergio Ciordiae ; Veró ; nica Ferná ; ndezg ; Maria Antonia Fortuñ ; oh ; Isabel Garcí ; a-Sá ; nchezi ; Rosario Martí ; nezj ; Maria Angeles Muñ ; ozk ; Clara Rodriguezl ; Nieves Domé ; nechb ; nieves.domenech.garcia@sergas.es" class="auth_mail" title="E-mail the corresponding author ; ProteoRed Spanish Biobanks Network
- 关键词：Plasma ; Proteomics ; Biobank ; Sample ; Pre-analytical variables
- 刊名：Journal of Proteomics
- 出版年：2017
- 出版时间：6 January 2017
- 年：2017
- 卷：150
- 期：Complete
- 页码：109-120
- 全文大小：5465 K
文摘
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The integrity of proteins is resistant to alteration by the preanalytical variables.
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Up to three freeze/thaw cycles have no effect on the integrity of proteins in plasma.
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Delayed processing of blood has no significant effect on the stability of proteins.