Antimicrobial photodynamic effect of extracts and oxoaporphine alkaloid isomoschatoline from Guatteria blepharophylla
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- 作者：Nathalia Luiza Andreazzaa ; nathilu@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Caroline Caramano de Lourenç ; oa ; Á ; lvaro José ; Hernandez-Tascoa ; Maria Lú ; cia B. Pinheirob ; Maria É ; lida Alves Stefanelloc ; Emmanoel Vilaç ; a Costab ; Marcos José ; Salvadora ; marcosjs@unicamp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：1 ; 3-DPBF ; 1 ; 3-diphenylisobenzofuran ; CFM ; confocal fluorescent microscopy ; GBCH ; bark hexane extract ; GBCM ; bark methanol extract ; GBFA ; alkaloid fraction ; HMBC ; Heteronuclear Multiple Bond Correlation ; HMQC ; Heteronuclear Multiple Quantum Coherence ; TLC ; thin layer chromatography ; TMS ; Tetramethylsilane ; SEM ; Scanning Electron Microscopy
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：160
- 期：Complete
- 页码：154-162
- 全文大小：1081 K
文摘
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Crude extracts, alkaloid fraction and isomoschatoline showed singlet oxygen production.
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Isomoschatoline photodynamic activity happens predominantly through type II mechanism.
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PDT effect against E. coli was significantly enhanced in the presence of additives.
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Greater energy doses and double sample's dosage also decreased microbial survival.