Fluoride decreased the sperm ATP of mice through inhabiting mitochondrial respiration
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- 作者：Zilong Suna ; b ; 1 ; Wen Zhangb ; 1 ; Xingchen Xuea ; b ; Yuliang Zhanga ; b ; Ruiyan Niua ; b ; Xuying Lia ; Baojun Lia ; Xiaowen Wangc ; wwxw11@163.com" class="auth_mail" title="E-mail the corresponding author ; Jundong Wanga ; b ; wangjd53@outlook.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Fluoride ; Sperm ; ATP ; Glycolysis ; Mitochondrial respiration
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：144
- 期：Complete
- 页码：1012-1017
- 全文大小：1524 K
文摘
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Fluoride exposure resulted in low mitochondria-derived ATP in mice sperm.
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Fluoride down-regulated the mRNA expressions of mt-Cytb and mt-COX2 in sperm.
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Fluoride caused ultrastructural defects and ETC disturbance in sperm mitochondria.