Epithelial Splicing Regulatory Protein 1 (ESRP1) is a new regulator of stomach smooth muscle development and plasticity
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- 作者：Sé ; bastien Sagnola ; Sté ; phane Marchala ; Yinshan Yangb ; Fré ; dé ; ric Allemandb ; Pascal de Santa Barbaraa ; Pascal.de-Santa-Barbara@inserm.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gastrointestinal tract ; Smooth muscle ; Chick ; RNA-binding protein ; FGF pathway ; ESRP1
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：414
- 期：2
- 页码：207-218
- 全文大小：10222 K
文摘
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ESRP1 is an early marker of developing and undifferentiated stomach mesenchyme.
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Sustained expression of ESRP1 alters SMC differentiation and FGFR2 splicing profile.
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ESRP1 and RBPMS2 synergistically promote SMC dedifferentiation.
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RBPMS2-mediated SMC dedifferentiation requires ESRP1.