Optimization of extraction method and evaluation of antileishmanial activity of oil and nanoemulsions of Pterodon pubescens benth. fruit extracts
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- 作者：É ; verton da Silva Santosa ; mlanecc@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Francielle Pelegrin Garciab ; Priscila Miyuki Outukia ; Jaqueline Hoscheida ; Paulo Roberto Nunes de Goesa ; Lú ; cio Cardozo-Filhoc ; d ; Celso Vataru Nakamuraa ; b ; Mara Lane Carvalho Cardosoa
- 关键词：Pterodon pubescens ; Nanoemulsion ; Geranylgeraniol ; Leishmania amazonensis ; Supercritical fluid extraction
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：170
- 期：Complete
- 页码：252-260
- 全文大小：1089 K
文摘
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Extracts were prepared using a supercritical fluid method.
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Supercritical extracts were more effective against L. amazonensis than conventional extracts.
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P. pubescens nanoemulsions showed a better selectivity index against parasites.