Kinetics of lentiviral vector transduction in human CD34+ cells
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- 作者：Naoya Uchida ; uchidan@nhlbi.nih.gov" class="auth_mail" title="E-mail the corresponding author ; Rashidah Green ; Josiah Ballantine ; Luke P. Skala ; Matthew M. Hsieh ; John F. Tisdale
- 刊名：Experimental Hematology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：44
- 期：2
- 页码：106-115
- 全文大小：1368 K
文摘
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We documented the kinetics of HIV-1 vector transduction in human CD34+ cells.
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Initiation of reverse transcription limits lentiviral transduction of CD34+ cells.
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Expansion medium improves transduction of human hematopoietic repopulating cells.