Genomic features of human limb specific enhancers
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- 作者：Shahid Alia ; Shahidbsb28@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Bibi Aminaa ; bbamina120@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Saneela Anwarb ; amirsanila@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Rashid Minhasa ; minhas61@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Nazia Parveena ; naziaahmad.nm@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Uzma Nawazc ; uzm_69@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Syed Sikandar Azamb ; ssazam@qau.edu.pk" class="auth_mail" title="E-mail the corresponding author ; Amir Ali Abbasia ; abbasiam@qau.edu.pk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Limbs ; Enhancers ; Genomics ; Regulatory networks ; Transcriptional factor ; Development ; disease
- 刊名：Genomics
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：108
- 期：3-4
- 页码：143-150
- 全文大小：766 K
文摘
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Specific target genes are pinpointed for human limb specific enhancers.
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Modular organization of enhancers may contribute in limb evolution.
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Range of action of limb specific enhancers is defined.
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Heterotypic interactions of multiple distinct TFs govern the limb morphogenesis.