Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
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- 作者：Yuanyuan Li1 ; 2 ; 8 ; Benjamin R. Sabari3 ; 8 ; Tatyana Panchenko3 ; 8 ; Hong Wen5 ; Dan Zhao1 ; 2 ; Haipeng Guan1 ; 2 ; Liling Wan3 ; He Huang6 ; Zhanyun Tang4 ; Yingming Zhao6 ; Robert G. Roeder4 ; Xiaobing Shi5 ; C. David Allis3 ; alliscd@mail.rockefeller.edu" class="auth_mail" title="E-mail the corresponding author ; Haitao Li1 ; 2 ; 7 ; lht@tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：21 April 2016
- 年：2016
- 卷：62
- 期：2
- 页码：181-193
- 全文大小：5119 K
文摘
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The YEATS domains constitute a family of histone crotonylation reader modules
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AF9 YEATS recognizes histone crotonylation via an extended aromatic sandwich pocket
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Bromodomains do not exhibit YEATS-like preference for crotonyllysine
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Histone crotonylation potentiates gene expression in an AF9 YEATS-dependent manner