Eric Davidson: Steps to a gene regulatory network for development

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• 作者：Ellen V. Rothenberg ^{evroth@its.caltech.edu" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Developmental Biology
• 出版年：2016
• 出版时间：15 April 2016
• 年：2016
• 卷：412
• 期：2_supp_S
• 页码：S7-S19
• 全文大小：1012 K

文摘

Eric Harris Davidson was a unique and creative intellectual force who grappled with the diversity of developmental processes used by animal embryos and wrestled them into an intelligible set of principles, then spent his life translating these process elements into molecularly definable terms through the architecture of gene regulatory networks. He took speculative risks in his theoretical writing but ran a highly organized, rigorous experimental program that yielded an unprecedentedly full characterization of a developing organism. His writings created logical order and a framework for mechanism from the complex phenomena at the heart of advanced multicellular organism development. This is a reminiscence of intellectual currents in his work as observed by the author through the last 30–35 years of Davidson's life.