Abnormal striatal resting-state functional connectivity in adolescents with obsessive-compulsive disorder
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- 作者：Gail A. Bernsteina ; berns001@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Bryon A. Muellerb ; muell093@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Melinda Westlund Schreinera ; westl110@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Sarah M. Campbella ; campb767@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Emily K. Regana ; rega0148@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Peter M. Nelsona ; d ; pmn12@psu.edu" class="auth_mail" title="E-mail the corresponding author ; Alaa K. Houria ; houri005@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Susanne S. Leea ; leexx310@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Alexandra D. Zagoloffa ; zagol001@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Kelvin O. Limb ; kolim@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Essa S. Yacoubc ; yaco0006@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Kathryn R. Cullena ; rega0026@umn.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Functional MRI ; Neuroimaging ; Striatum ; Insula ; Operculum
- 刊名：Psychiatry Research: Neuroimaging
- 出版年：2016
- 出版时间：30 January 2016
- 年：2016
- 卷：247
- 期：Complete
- 页码：49-56
- 全文大小：420 K
文摘
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Adolescents with OCD show abnormal striatal resting-state functional connectivity.
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Teens with OCD have lower connectivity between putamen and a single cluster of cortical areas.
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Cluster included parts of the orbitofrontal cortex, inferior frontal gyrus, insula, and operculum.