Electrocorticography reveals beta desynchronization in the basal ganglia-cortical loop during rest tremor in Parkinson's disease
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- 作者：Salman E. Qasima ; salman.qasim@columbia.edu" class="auth_mail" title="E-mail the corresponding author ; Coralie de Hemptinneb ; Coralie.Dehemptinne@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Nicole C. Swannb ; Nicole.Swann@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Svjetlana Miocinovicc ; Svjetlana.Miocinovic@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Jill L. Ostremc ; Jill.Ostrem@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Philip A. Starrb ; Philip.Starr@ucsf.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Parkinson's disease ; Electrocorticography (ECoG) ; Tremor ; Basal ganglia ; Deep brain stimulation (DBS)
- 刊名：Neurobiology of Disease
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：86
- 期：Complete
- 页码：177-186
- 全文大小：1177 K
文摘
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We recorded cortical ECoG and STN LFP in PD patients during rest tremor.
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Rest tremor decreased beta synchronization in the basal ganglia-cortical loop.
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Cortical activity during rest tremor may distinguish tremor from voluntary movement.
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Rest tremor may partly compensate for excessive beta band synchronization in PD.