Mass transfer, gas hold-up and cell cultivation studies in a bottom agitated draft tube reactor and multiple impeller Rushton turbine configuration
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- 作者：Petri Tervasmä ; kia ; petri.tervasmaki@oulu.fi" class="auth_mail" title="E-mail the corresponding author ; Marko Latva-Kokkob ; Sanna Taskilaa ; Juha Tanskanena
- 关键词：Stirred tank ; Draft tube ; KLa ; Hold-up ; Yeast cultivation ; Bioreactor
- 刊名：Chemical Engineering Science
- 出版年：2016
- 出版时间：22 November 2016
- 年：2016
- 卷：155
- 期：Complete
- 页码：83-98
- 全文大小：4344 K
文摘
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OKTOP®9000 draft tube reactor was utilized in a cell cultivation and mixing study.
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More uniform DO-profile was measured for OKTOP® reactor in cell cultivation.
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Draft tube reactor achieved higher kLa than regular STR with similar agitation power.
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EIT-measurements showed differences in local gas hold-up and gas flow regimes.