A Cue for Driving Large-Scale Cell Movement
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文摘
The earliest cell movements that initiate gastrulation in the vertebrate embryo have always fascinated embryologists, but signals controlling this large-scale morphogenesis where nearly all cells move have been elusive. Reporting in Developmental Cell, Szabó et al. (2016) uncover a mechanism for morphogenesis based on complement system C3a/C3aR-directed chemotaxis.

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