MiR-146a modulates macrophage polarization by inhibiting Notch1 pathway in RAW264.7 macrophages
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- 作者：Cheng Huanga ; b ; c ; Xue-jiao Liua ; b ; c ; 1 ; QunZhoua ; b ; c ; Juan Xiea ; b ; c ; Tao-tao Maa ; b ; c ; Xiao-ming Menga ; b ; c ; Jun Lia ; b ; c ; lj@ahmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; liuxuejiao0615@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arg1 ; arginase 1 ; iNOS ; inducible NO synthase ; IL-10 ; interleukin-10 ; miRNA ; microRNAs ; PPARγ ; peroxisome proliferator-activated receptor γ ; TNF-α ; tumor necrosis factor alpha
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：32
- 期：Complete
- 页码：46-54
- 全文大小：1296 K
文摘
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MiR-146a modulated macrophage polarization.
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MiR-146a inhibited Notch1 pathway.
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MiR-146a enhanced the activation of M2 macrophages.