Reference values of MostGraph measures for middle-aged and elderly Japanese individuals who participated in annual health checkups

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• 作者：Yuki Abe^a ; ^{yu-abe@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yoko Shibata^a ; ^{shibata@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Akira Igarashi^a ; ^{akigaras@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Sumito Inoue^a ; ^{sinoue@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Kento Sato^a ; ^{k-sato@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Masamichi Sato^a ; ^{m-satoh@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Takako Nemoto^a ; ^{n.takako@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Maki Kobayashi^a ; ^{m-kobayashi@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Michiko Nishiwaki^a ; ^{m-nishi@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Tomomi Kimura^a ; ^{tomomi-i@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yoshikane Tokairin^a ; ^{ytokair@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Takamasa Kayama^b ; ^{pulmoyamagata@outlook.jp" class="auth_mail" title="E-mail the corresponding author} ; Isao Kubota^a ; ^{ikubota@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}
• 关键词：FOT ; forced oscillation technique ; R5 ; resistance at 5  ; Hz ; R20 ; resistance at 20  ; Hz ; R5&minus ; R20 ; difference between R5 and R20 ; X5 ; respiratory system reactance at 5  ; Hz ; Fres ; resonant frequency ; ALX ; low frequency reactance area.
• 刊名：Respiratory Investigation
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：54
• 期：3
• 页码：148-155
• 全文大小：1290 K

文摘

The forced oscillation technique (FOT) can measure respiratory system resistance and reactance under tidal volume respiration. MostGraph is a device that incorporates the FOT and enables the immediate, three-dimensional visualization of resistance and reactance parameters. The aim of this study was to establish MostGraph reference values for middle-aged and elderly Japanese individuals.

Methods

From 2004 to 2006, 3253 subjects living in Takahata, Yamagata underwent spirometry. Of these, 872 again underwent spirometry in 2011, and 784 (368 men, ages 46–89 years; 416 women, ages 47–90 years) underwent FOT examinations using MostGraph-01.

Results

In this study population, 19.0% of the men and 91.5% of the women were life-long never smokers. Abnormal spirometric findings were observed in 30.2% of the men and 14.6% of the women. Although the respiratory system resistance and reactance parameters obtained using MostGraph were not distributed normally, normal distribution was achieved via natural logarithm (R5, R20, Fres, and ALX), square root (R5-R20), or exponential (X5) transformation. Furthermore, the transformed values were converted back to the actual values after determining the values representing one and two standard deviations from the mean.

Conclusion

Respiratory system resistance and reactance reference values were determined using MostGraph in middle-aged and elderly Japanese individuals who participated in annual health checkups.