Recombinant expression of porcine lactoferrin peptide LF-6 with intein technology and its immunomodulatory function in ETEC K88-infected mice
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- 作者：Qin Jianga ; 84413414@qq.com" class="auth_mail" title="E-mail the corresponding author ; Haiwen Zhangb ; 007zhanghaiwen@163.com" class="auth_mail" title="E-mail the corresponding author ; Yonggang Xiea ; xyg285@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yizhen Wanga ; zhanghwas@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antibacterial peptide ; Recombinant expression ; Intein system ; Enterotoxigenic Escherichia coli-K88 ; Lactoferricin P ; Immunomodulatory
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：181-191
- 全文大小：1668 K
文摘
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Designed LF-6 had distinctive structure compared with parental peptide LFP-20.
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Expression LF-6 by intein system is no enzymatic and self-cleaving process.
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LF-6 is not only confined to antibacterial but immune regulation potential.