Ganglionic acetylcholine receptor autoantibodies in patients with Guillain-Barré syndrome
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- 作者：Shunya Nakanea ; b ; 1 ; nakaneshunya@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Osamu Higuchia ; 1 ; osmhgc@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yukihiro Hamadac ; hamashi1207@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author ; Yasuhiro Maedaa ; b ; d ; yas.maeda@hotmail.co.jp" class="auth_mail" title="E-mail the corresponding author ; Akihiro Mukainod ; e ; a.mukaino@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Waka Sakaib ; wakasakai@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Susumu Kusunokic ; kusunoki-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hidenori Matsuob ; hidenori@hosp.go.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Guillain-Barré ; syndrome ; Anti-ganglionic acetylcholine receptor autoantibodies ; Autonomic dysfunction ; Anti-glycolipid antibodies
- 刊名：Journal of Neuroimmunology
- 出版年：2016
- 出版时间：15 June-15 July 2016
- 年：2016
- 卷：295-296
- 期：Complete
- 页码：54-59
- 全文大小：462 K
文摘
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We reported the prevalence of autoantibodies against ganglionic acetylcholine receptor in GBS.
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Sera from GBS patients in Japan were tested with luciferase immunoprecipitation systems (LIPS).
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11.2% (9 of 80) of the sera samples from patients with GBS were positive for autoantibodies.
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The anti-gAChR antibodies could mediate the autonomic dysfunction involved in the mechanisms of GBS.