Prediction of clinical outcomes using the pyrolysis, gas chromatography, and differential mobility spectrometry (Py-GC-DMS) system
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- 作者：Arati A. Inamdara ; AInamdar@HackensackUMC.org" class="auth_mail" title="E-mail the corresponding author ; Parag Borgaonkarb ; borgaonkar.parag@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yvonne K. Remachea ; YRemache@HackensackUMC.org" class="auth_mail" title="E-mail the corresponding author ; Shalini Nairb ; shalini.nair@acbirox.com" class="auth_mail" title="E-mail the corresponding author ; Waleed Maswadehc ; wmmaswad2001@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Amit Limayeb ; al.limaye@logistic-solutions.com" class="auth_mail" title="E-mail the corresponding author ; Arnold P. Snyderc ; Arnold.P.Snyder.civ@mail.mil" class="auth_mail" title="E-mail the corresponding author ; Andrew Pecorad ; APecora@HackensackUMC.org" class="auth_mail" title="E-mail the corresponding author ; Andre Goyd ; AGoy@HackensackUMC.org" class="auth_mail" title="E-mail the corresponding author ; K. Stephen Suha ; KSuh@HackensackUMC.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：bcl-1 ; b-cell lymphoma-isoform 1 ; CDK4 ; Cyclin dependent kinase 4 ; CDKN2A ; cyclin dependent kinase inhibitor 2A ; MIB-1 ; mindbomb 1 ; SOX-11 ; sry-related HMG box ; IL-2Rα ; interleukin-2 receptor alpha ; IL-8 ; interleukin-8 ; MIP-1β ; macrophage inflammatory protein-1 beta
- 刊名：Journal of Analytical and Applied Pyrolysis
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：119
- 期：Complete
- 页码：189-198
- 全文大小：2947 K
文摘
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Role of pyrolysis, gas chromatography, and differential mobility spectrometry system for human diseases was explored.
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Using Mantle cell lymphoma as a conceptual model, ionized spectral signals were generated via this system The signal data upon processing with multivariable algorithm to predicted the outcome of the disease with 90% accuracy.
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Py-GS-DMS technology provides an independent strategy to enhancing clinical decision-making towards treatment of the diseases.