Protocadherin 10 inhibits cell proliferation and induces apoptosis via regulation of DEP domain containing 1 in endometrial endometrioid carcinoma
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- 作者：Yihua Yanga ; 1 ; yangyihua@glmc.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yan Jiangb ; 1 ; 260070985@qq.com" class="auth_mail" title="E-mail the corresponding author ; Man Jiangb ; jiangmanman@126.com" class="auth_mail" title="E-mail the corresponding author ; Jiamiao Zhanga ; zhangxq1006@163.com" class="auth_mail" title="E-mail the corresponding author ; Bing Yangb ; 1224462833@qq.com" class="auth_mail" title="E-mail the corresponding author ; Yuanping Sheb ; shelittle@163.com" class="auth_mail" title="E-mail the corresponding author ; Wanxue Wanga ; 854777399@qq.com" class="auth_mail" title="E-mail the corresponding author ; Yan Dengc ; shrilly@cuhk.edu.hk" class="auth_mail" title="E-mail the corresponding author ; Yuan Yeb ; glyy169@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：EEC ; PCDH10 ; DEPDC1 ; Cell growth ; Apoptosis ; Caspase
- 刊名：Experimental and Molecular Pathology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：100
- 期：2
- 页码：344-352
- 全文大小：1297 K
文摘
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PCDH10 is down-regulated in EEC clinical tissues.
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PCDH10 functions as a tumor suppressor in EEC.
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DEPDC1 is a downstream mediator of PCDH10.
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DEPDC1 promotes cell proliferation in EEC.
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PCDH10 induces apoptosis via caspase signaling.