Efficient ring opening of epoxides with trimethylsilyl azide and cyanide catalyzed by erbium(III) triflate

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• 作者：Antonio Procopio ; Paola Costanzo ; Renato Dalpozzo ; Loredana Maiuolo ; Monica Nardi ; Manuela Oliverio
• 关键词：Erbium(III) triflate ; Epoxide ring-opening ; Cyanohydrins ; Azido alcohols
• 刊名：Tetrahedron Letters
• 出版年：2010
• 出版时间：29 September 2010
• 年：2010
• 卷：51
• 期：39
• 页码：5150-5153
• 全文大小：607 K

文摘

Epoxides can be opened under neutral conditions with TMSN₃ and TMSCN in the presence of catalytic amounts of Lewis acid, affording the corresponding ring-opened compounds in high yields.