Ipomopsin and hymenain, two biscoumarins from seeds of Hymenaea courbaril

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• 作者：Kelly Simõ ; es ; Jiang Du ; Rosemeire A.B. Pessoni ; Elaine M. Cardoso-Lopes ; Jorge M. Vivanco ; Frank R. Stermitz ; Marcia R. Braga
• 关键词：Hymenaea courbaril ; Leguminosae ; Scopoletin ; Biscoumarins ; Free radical scavenging activity ; 7-Hydroxy-6 ; 6′ ; -dimethoxy-3 ; 7′ ; -dicoumarinyl ether
• 刊名：Phytochemistry Letters
• 出版年：2009
• 出版时间：29 April 2009
• 年：2009
• 卷：2
• 期：2
• 页码：59-62
• 全文大小：155 K

文摘

A new biscoumarin (7-hydroxy-6,6′-dimethoxy-3,7′-dicoumarinyl ether), named hymenain (1) and the known biscoumarin ipomopsin (2) were isolated from the germinated seeds of Hymenaea courbaril var. stilbocarpa. Their structures were elucidated by spectroscopic methods. Scopoletin was also detected in the extracts by TLC and GC–MS analyses. Hymenain and ipomopsin showed direct scavenging effect on a stable free radical, 2,2-diphenyl-1-picryl-hydrazyl (DPPH) with the EC₅₀ values of 100 and 300 μM, respectively.