Implication et modes d'action des agents infectieux dans la formation de la plaque d'athérome. Infection et athérosclérose
详细信息 查看全文
- 作者：Lizard ; G. ; Gambert ; P.
- 关键词：agents infectieux ; athé ; rosclé ; rose ; Chlamydia pneumoniae ; coxsakievirus A ; Helicobacter pylori ; Porphyromonas gingivalis ; Streptococcus sanguis ; virus herpè ; s simplex ; virus de l'hé ; patite A ; atherosclerosis ; Chlamydia pneumoniae
- 刊名：Pathologie Biologie
- 出版年：2001
- 出版时间：2001
- 年：2001
- 卷：49
- 期：10
- 页码：824-829
- 全文大小：74.2 K
文摘
Different kinds of infectious agents seem to be implied in the atherosclerotic process. Indeed, some bacteria and viruses have been identified in atherosclerotic lesions: Chlamydia pneumoniae, Helicobacter pylori, Streptococcus sanguis, Porphyromonas gingivalis, herpes simplex viruses type 1 and 2, coxsakievirus B and hepatitis virus A. By their ability to induce antigenic and functionnal changes in the cells of the vascular wall (endothelial cells, smooth muscle cells, monocytes/macrophages, and fibroblasts) and to stimulate immune response as well as oxidative stress, it is more and more tempting to speculate that infectious agents probably play key roles in the initiation and in the formation of atherosclerotic plaques in certain patients.