Autologous Skull Bone Flap Sterilization After Decompressive Craniectomy: An Update

详细信息    查看全文

• 作者：Paolo Missori¹ ; Daniele Marruzzo¹ ; ^{danielemarruzzo@yahoo.it" class="auth_mail" title="E-mail the corresponding author} ; Sergio Paolini² ; Arsen Seferi³ ; Marco Fricia⁴ ; Massimo Chiara¹ ; Valeria Palmarini¹ ; Maurizio Domenicucci¹
• 关键词：Bone ; Cranioplasty ; Decompressive craniectomy ; Intracranial hypertension ; Sterilization
• 刊名：World Neurosurgery
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：90
• 期：Complete
• 页码：478-483
• 全文大小：1082 K

文摘

To report new results with ethylene oxide sterilization and new experiences with autogenous bone flaps autoclaved at a high or low temperature for preservation of a bone flap after decompressive craniectomy.

Methods

In 45 patients who underwent a decompressive craniectomy, we determined bone flap preservation with ethylene oxide and with high- or low-temperature autoclave sterilization.

Results

The bone flap was repositioned after a mean of 10 weeks in the ethylene oxide group and after 6 weeks in the other sterilization groups. A bone flap infection developed in 1 patient (2%), which required removal and subsequent methyl methacrylate cranioplasty. In 1 child, the bone flap had partially reabsorbed after 12 months. In all other patients, esthetic results were good after an average follow-up of 42 months. At follow-up, computed tomography or magnetic resonance imaging of the bone flap showed preservation of structural features with apparent fusion and revitalization at the bone flap margins.

Conclusions

Ethylene oxide and high- or low-temperature autoclave bone sterilization techniques for the preservation of autologous bone flaps after decompressive craniectomy were safe, rapid, and inexpensive.