Application of CRISPR-mediated genome engineering in cancer research

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• 作者：Volkan I. Sayin ; Thales Papagiannakopoulos ; ^{papagt01@nyumc.org}
• 关键词：CRISPR ; Cas9 ; Genome engineering ; Cancer ; Mouse models
• 刊名：Cancer Letters
• 出版年：2017
• 出版时间：28 February 2017
• 年：2017
• 卷：387
• 期：Complete
• 页码：10-17
• 全文大小：1727 K
• 卷排序：387

文摘

In vitro modeling of genetic variants using CRISPR/Cas9. Somatic genome engineering with CRISPR/Cas9. CRISPR/Cas9-based effectors. CRISPR/Cas9-based genetic screens. Looking forward: Caveats and future applications of the CRISPR/Cas9 system in cancer biology.