Some pharmacological effects of Tityus obscurus venom in rats and mice

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• 作者：Andria de Paula Santos-da-Silva^a ; ¹ ; Denise Maria Candido^b ; Ana Leonor A. Nencioni^a ; Louise F. Kimura^c ; ² ; Jos&eacute ; P. Prezotto-Neto^c ; ³ ; Katia Cristina Barbaro^c ; Hipó ; crates M. Chalkidis^d ; Valquí ; ria Abrã ; o Coronado Dorce^a ; ^{vdorce@butantan.gov.br}
• 关键词：Scorpion venom ; Tityus obscurus ; Envenomation
• 刊名：Toxicon
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：126
• 期：Complete
• 页码：51-58
• 全文大小：882 K
• 卷排序：126

文摘

Tityus obscurus is the main scorpion responsible for accidents in the Amazon region. Tityus obscurus, similar to T. serrulatus venom, exerted edematogenic activity in mice. Tityus obscurus venom caused hemorrhagic patches in the lung of rats. Both nociceptive and lethal activities of T. obscurus venom were lower than those caused by T. serrulatus venom in mice.