Safety and protective efficacy of a spiC and crp deletion mutant of Salmonella gallinarum as a live attenuated vaccine for fowl typhoid
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- 作者：Zhao Chenga ; Junlei Yina ; Xilong Kanga ; Shizhong Genga ; Maozhi Hub ; Zhiming Pana ; zmpan@yzu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xinan Jiaoa ; jiao@yzu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Salmonella gallinarum ; Fowl typhoid ; Live attenuated vaccine ; Safety ; Protective efficacy
- 刊名：Research in Veterinary Science
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：107
- 期：Complete
- 页码：50-54
- 全文大小：376 K
文摘
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1009ΔspiCΔcrp can induce humoral and cellular immune responses.
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1009ΔspiCΔcrp did no harm to the chickens or produce any side effects.
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1009ΔspiCΔcrp can offer efficient protection against acute systemic FT.
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1009ΔspiCΔcrp can be used as a live attenuated vaccine for FT.