Competitive replication kinetics and pathogenicity in pigs co-infected with historical and newly invading classical swine fever viruses

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• 作者：Yu-Liang Huang^a ; ¹ ; ^{ylhuang@mail.nvri.gov.tw} ; Ming-Chung Deng^a ; ¹ ; ^{mcdeng@mail.nvri.gov.tw} ; Kuo-Jung Tsai^a ; ^{krtsai@mail.nvri.gov.tw} ; Hsin-Meng Liu^a ; ^{casiopea963@yahoo.com.tw} ; Chin-Cheng Huang^b ; ^{cch@mail.coa.gov.tw} ; Fun-In Wang^c ; ^{fiwangvm@ntu.edu.tw} ; Chia-Yi Chang^a ; ^{cychang@mail.nvri.gov.tw}
• 关键词：Classical swine fever virus ; Genotype ; Virus shift ; Viral replication ; Pathogenesis
• 刊名：Virus Research
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：228
• 期：Complete
• 页码：39-45
• 全文大小：1049 K
• 卷排序：228

文摘

CSFV genotypes 2.1 and 3.4 were co-inoculated both in vivo and in vitro. The newly invading CSFV genotype 2.1 replicated more efficiently than genotype 3.4. This study demonstrates a possible explanation of virus shift in the field.