The C-terminal binding protein (CTBP-1) regulates dorsal SMD axonal morphology in Caenorhabditis elegans
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- 作者：A. Reid&dagger ; ; T.J. Sherry ; D. Yü ; cel&Dagger ; ; E. Llamosas¶ ; ; H.R. Nicholas ; hannah.nicholas@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：CGC ; Caenorhabditis Genetics Centre ; CtBPs ; C-terminal binding proteins ; dCtBP ; Drosophila CtBP ; L4 ; fourth larval ; NGM ; Nematode Growth Medium ; SMDD ; dorsal SMD
- 刊名：Neuroscience
- 出版年：2015
- 出版时间：17 December 2015
- 年：2015
- 卷：311
- 期：Complete
- 页码：216-230
- 全文大小：1049 K
文摘
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CTBP-1 regulates exploration behavior in Caenorhabditis elegans.
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CTBP-1 regulates dorsal SMD (SMDD) axonal morphology.
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RAB-3 localizes to the mispositioned portion and distal tip of SMDD axons of ctbp-1 mutant animals.
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The penetrance of the axonal morphology phenotype increases in adult ctbp-1 mutants.
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CTBP-1 is expressed in lad-2-expressing head neurons which include the SMDD neurons.