Association of estradiol on expression of melanocortin receptors and their accessory proteins in the liver of chicken (Gallus gallus)

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• 作者：Junxiao Ren^a ; ¹ ; Yanmin Li^a ; ¹ ; Naiyi Xu^a ; Hong Li^a ; Cuicui Li^a ; Ruili Han^a ; ^b ; ^c ; Yanbin Wang^a ; ^b ; ^c ; Zhuanjian Li^a ; ^b ; ^c ; Xiangtao Kang^a ; ^b ; ^c ; Xiaojun Liu^a ; ^b ; ^c ; ^{xjliu2008@hotmail.com} ; Yadong Tian^a ; ^b ; ^c ; ^{ydtian111@163.com}
• 关键词：Chicken ; Melanocortin receptors ; Melanocortin receptor accessory proteins ; 17β-Estradiol
• 刊名：General and Comparative Endocrinology
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：182-190
• 全文大小：2514 K
• 卷排序：240

文摘

MRAP and MRAP2 were conserved between species. MRAP and MCRs were expressed in adrenal gland, and also in other tissues in chicken. Only MRAP and MC5R expressed in chicken liver. The expression of MRAP was regulated by estrogen in vivo and in vitro. MRAP might play its biological role in a different way rather than forming an MRAP/MC2R complex.