A new flavone sulfonic acid from Phyllanthus urinaria
详细信息 查看全文
- 作者：Nguyen Van Thanh ; Phan Thi Thanh Huong ; Nguyen Hoai Nam ; Nguyen Xuan Cuong ; Nguyen Phuong Thao ; Bieke Dejaegher ; Andrea Gordien ; Yvan V ; er Heyden ; Jo毛lle Quetin-Leclercq ; Chau Van Minh
- 关键词：Phyllanthus urinaria ; Euphorbiaceae ; Cytotoxic activity
- 刊名：Phytochemistry Letters
- 出版年：February, 2014
- 年：2014
- 卷：7
- 期：Complete
- 页码：182-185
- 全文大小：302 K
文摘
One new flavone derivative, urinariaflavone (1), and eight known compounds (2-9) were isolated from the methanolic extract of Phyllanthus urinaria L. leaves. Their structures were established by MS, 1D and 2D NMR experiments, and comparison with literature data. All isolated compounds were tested for their cytotoxic activity against CHO (Chinese hamster ovary) and J774 (Murine macrophage) cell lines. Cytotoxic effects (IC50s 鈭?#xA0;6.00-41.30 渭M) on both cell lines were observed for compounds 4, 5, and 7.