Physiological Techniques and Pulmonary Hypertension - Left Heart Disease

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• 作者：Manyoo Agarwal^a ; ^b ; Aaron B. Waxman^b ; ^c ; ^{abwaxman@partners.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：ADMA ; asymmetric dimethylarginine ; AUC ; area under the curve ; CaO2 ; arterial oxygen concentration ; C-Echo ; cardiopulmonary exercise testing-echocardiography ; CI ; cardiac index ; CO ; cardiac output ; Combined PH ; precapillary-postcapillary PH ; CPET ; cardiopulmonary exercise testing ; CvO2 ; venous oxygen concentration ; dPAP ; diastolic pulmonary artery pressure ; DPG ; diastolic pressure gradient ; EF ; ejection fraction ; ePAWP ; end-expiratory pulmonary artery wedge pressure ; eNO ; exhaled nitric oxide ; Gr
• 刊名：Progress in Cardiovascular Diseases
• 出版年：2016
• 出版时间：July-August 2016
• 年：2016
• 卷：59
• 期：1
• 页码：30-41
• 全文大小：682 K

文摘

Group 2 Pulmonary hypertension (PH) is associated with left heart disease (LHD;Group 2 PH) and is the most common form of PH. Group 2 PH represents an important subgroup of patients with LHD where the development of PH leads to a significant increase in morbidity and mortality. Early diagnosis may provide an opportunity to intervene and significantly delay progression. In addition to clinical suspicion, several approaches including hemodynamic assessment, exercise testing, and imaging techniques play an important role in better disease characterization and management. Here, we review the role of physiologic based hemodynamic and exercise assessments of Group 2 PH patients.