Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus)
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- 作者：Ali Karamia ; alikaramiv@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Nicholas Romanob ; Tamara Gallowayc ; Hazilawati Hamzahd
- 关键词：MPs ; Microplastics ; PE ; Polyethylene ; LDPE ; Low-density polyethylene ; Phe ; Phenanthrene ; GnRH ; Gonadotropin-releasing hormone ; tph2 ; Tryptophan hydroxylase2 ; cyp19a2 ; Brain aromatase ; foxl2 ; Forkhead box L2 ; ftz-f1 ; Fushi tarazu-factor 1 ; 11β-hsd2 ; 11 β-hydroxysteroid dehydrogenase type 2 ; TP ; Total protein ; AST ; Aspartate aminotransferase ; ALT ; Alanine aminotransferase ; LDH ; Lactate dehydrogenase ; ALP ; Alkaline phosphatase ; γGT ; Gamma-glutamyl transpeptidase ; HDL ; High-density lipoprotein ; LDL
- 刊名：Environmental Research
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：151
- 期：Complete
- 页码：58-70
- 全文大小：3886 K
文摘
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Fish were exposed to virgin microplastics (MPs) alone or in combination with phenanthrene (Phe).
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Substantial histopathological changes occurred in the gill and liver.
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Virgin MPs alone or loaded with Phe altered blood biochemical parameters.
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Virgin or Phe-loaded MPs changed the transcription of some of the reproductive-axis genes.