Nicotine metabolism was examined in alcoholics over 7 weeks of alcohol treatment.
Rate of nicotine metabolism was assessed using the nicotine metabolite ratio (NMR).
NMR was significantly higher at week 1 compared to week 7 after alcohol cessation.
Suggests that chronic alcohol abuse increased the rate of nicotine metabolism.
Accelerated rate of nicotine metabolism decreased 4–7 weeks after alcohol cessation in alcoholics.