Sepiolite and palygorskite-underpinned regulation of mRNA expression of pro-inflammatory cytokines as determined by a murine inflammation model

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• 作者：Cynthia Paola Ló ; pez-Pacheco^a ; ^b ; Antonio Nieto-Camacho^c ; Luis Zarate-Reyes^a ; Emilia Garcí ; a-Romero^d ; ^e ; Mercedes Suá ; rez^f ; Stephan Kaufhold^g ; Eduardo Garcí ; a Zepeda^a ; ^b ; ¹ ; ^{garciaze@unam.mx} ; Javiera Cervini-Silva^h ; ⁱ ; ^j ; ^{jcervini@correo.cua.uam.mx}
• 关键词：Therapeutic ; Regulation ; Cytokines ; Expression of IL-1 and TNF-α
• 刊名：Applied Clay Science
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：137
• 期：Complete
• 页码：43-49
• 全文大小：488 K
• 卷排序：137

文摘

Sepiolite and palygorskite downregulate expression of IL-1 and TNF-α. Sepiolite and palygorkite regulate infiltration of neutrophils to skin Clay minerals modulate the inflammatory environment since its initial phase. Clay minerals alter the mRNA expression of four pro-inflammatory cytokines. These clay minerals may be used as a therapeutic tool against inflammatory diseases.