Enhanced yield of ethylene glycol production from d-xylose by pathway optimization in Escherichia coli

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• 作者：Rhudith B. Cabulong^a ; ¹ ; Kris Ni&ntilde ; o G. Valdehuesa^a ; ¹ ; Kristine Rose M. Ramos^a ; Grace M. Nisola^a ; Won-Keun Lee^b ; Chang Ro Lee^b ; Wook-Jin Chung^a ; ^{wjc0828@gmail.com}
• 关键词：Aldehyde reductase ; Ethylene glycol ; Dahms pathway ; d-xylose ; Metabolic engineering ; YjgB
• 刊名：Enzyme and Microbial Technology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：97
• 期：Complete
• 页码：11-20
• 全文大小：3142 K
• 卷排序：97

文摘

Enhanced EG production using a combination of simple metabolic strategies. Tight control of Xdh expression reduced d-xylonate accumulation. YjgB was identified as the best aldehyde reductase for EG production. Greatly enhanced EG yield up to 98% of theoretical.