A versatile platform of magnetic microspheres loaded with dual-anticancer drugs for drug release
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- 作者：Xiaodan Wanga ; b ; Xiaoyan Jinga ; Xiangyu Zhangc ; Qi Liua ; ; Jingyuan Liud ; Dalei Songa ; Jun Wanga ; d ; zhqw1888@sohu.com" class="auth_mail" title="E-mail the corresponding author ; Lianhe Liud
- 关键词：Biomaterials ; Magnetic materials ; Polymers ; Infrared spectroscopy
- 刊名：Materials Chemistry & Physics
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：177
- 期：Complete
- 页码：213-219
- 全文大小：1416 K
文摘
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A platform was constituted including hydrophilic drug (DOX) and hydrophobic drug (Cur) simultaneously.
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The magnetic microspheres show excellent magnetite content.
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Microspheres loaded with drug showed a certain sustained release and higher release rate.
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Microspheres loaded with dual-anticancer drugs are nontoxic to live cells and have high cell cytotoxicity.